I-Pyrrolo[2,3-d]pyrimidin-4-ol 98%min
Iphuzu elincibilikayo: 345-348°C
Indawo yokubilisa: 473.1±18.0 °C(Kubikezelwe)
Ukuminyana: 1.62± 0.1g /cm3(Kubikezelwe)
I-RTECS: UY9440000
Izimo zesitoreji ngu-2-8°C
Ukunyibilika: Kuncibilika ku-dimethyl sulfoxide.
Ifomu: Okuqinile
I-acidity coefficient (pKa) 11.99 + 0.20 (Kubikezelwe)
Ukuzwela: Umswakama & Okunsundu Okukhanyayo
InChIKeyFBMZEITWVNHWJW UHFFFAOYSA - N
Uphawu lwengozi (GHS):
Igama lesixwayiso: Isexwayiso
Incazelo yengozi: H317-H319
Izinyathelo zokuphepha: P280-P302+P352-P305+P351+P338
Ikhodi Yekilasi Lengozi: 36-43
Imiyalo yokuphepha: 26-36/37
I-WGK Germany : 3
Inothi Lengozi :Iyacasula
Ikhodi ye-HS: 29335990
Gcina endaweni epholile. Gcina isitsha sivaliwe futhi ugcine endaweni eyomile, engenawo umoya.
Izinga lokushisa elinconyiwe lesitoreji: 2-8 °C
Sebenza ngaphansi kwe-nitrogen ukuze ugweme umswakama. Izwela ukushisa, ukukhanya kanye nomswakama ogcinwe ku-nitrogen.
Ipakishwe ku-25kg/drum, ifakwe isikhwama sepulasitiki esiphindwe kabili, noma ipakishwe ngokwezidingo zamakhasimende.
Okuphakathi, Pharmaceutical Intermediate
Kuyi-prodrug ye-xanthine oxidase ecushiwe i-thymidine phosphorylase inhibitors.
Kuyi-organic synthesis kanye ne-Pharmaceutical Intermediate, ikakhulukazi esetshenziswa ekukhiqizeni i-tofacitinib, i-barricitinib nezinye izidakamizwa ezilwa nomdlavuza ohlelweni lokuhlanganisa amakhemikhali nemithi.
Isimo Sesitoreji
Gcina esitsheni esingangenisi umoya ekamelweni lokushisa.
Iphakheji
Ipakishwe ku-25kg/drum, ifakwe isikhwama sepulasitiki esiphindwe kabili, noma ipakishwe ngokwezidingo zamakhasimende.
Izinkambu Zohlelo
Okuphakathi, Pharmaceutical Intermediate
INTO YOKUHLOLA | INKCAZO |
Izici | Okuqinile okumhlophe kuya kokumhlophe |
Okuqukethwe Amanzi | ≤0.5% |
Ubumsulwa(nge-HPLC) | ≥98.0% |
I-Assay(nge-HPLC) | ≥98.0% |
INOMBOLO YE-CAS: 67831-84-9
Igama lomkhiqizo: 4H-Pyrrolo[2,3-d]pyrimidin-4-one,1,2,3,7-tetrahydro-2-thioxo-
Ifomula yemolekyuli: C6H5N3OS
INOMBOLO YECAS:7400-06-8
Igama lomkhiqizo: 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol
Ifomula yemolekyuli:C10H17N3O3
INOMBOLO YECAS.:56-86-0
Igama lomkhiqizo: L-glutamic acid
Ifomula yemolekyuli:C5H9NO4
Inombolo ye-CAS: 52133-67-2
Igama Lomkhiqizo: Ethyl 2-cyano-4,4-diethoxybutyrate
Ifomula yemolekyuli: C11H19NO4
Inombolo ye-CAS: 7400-05-7
Igama Lomkhiqizo:4(1H)-Pyrimidinone,6-amino-5-(2,2-diethoxyethyl)-2,3-dihydro-2-thioxo-
Ifomula yemolekyuli:C10H17N3O3S
Inombolo ye-CAS: 3680-69-1
Igama Lomkhiqizo:4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Ifomula yemolekyuli:C6H4ClN3
Inombolo ye-CAS: 346599-63-1
Igama lomkhiqizo: 4-Chloro-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one
Ifomula yemolekyuli:C6H4ClN3O
Inombolo ye-CAS: 941685-26-3
Igama lomkhiqizo:4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
Ifomula yemolekyuli:C12H18ClN3OSi
Inombolo ye-CAS: 186519-89-1
Igama lomkhiqizo: 4-chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
Ifomula yemolekyuli:C12H8ClN3O2S
Inombolo ye-CAS: 3680-69-1
Igama Lomkhiqizo:4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Ifomula yemolekyuli:C6H4ClN3