I-Pyrrolo[2,3-d]pyrimidin-4-ol 98%min

Ulwazi Oluyisisekelo:

Igama Lomkhiqizo: I-Pyrrolo[2,3-d]pyrimidin-4-ol
Amazwi afanayo: 7-DEAZAHYPOXANTHINE, 7-DEAZA-6-HYDROXY PURINE; I-Pyrrolo[2,3-d]pyrimidin-4-ol, 1,7-Dihydro-pyrrolo[2,3-d...,7H-Pyrrolo[2,3-d]pyrimidin-4-ol
7H-PYRROLO[2,3-D]PYRIMIDIN-4-OL,4H-Pyrrolo[2,3-d]pyriMidin-4-one,4-HYDROXYPYRROLO[2,3-D]PYRIMIDINE, 4-hydroxypyrrolo[2, 3-d]pyrimidine,3H-PYRROLO[2,3-D]PYRIMIDIN-4(7H)-ONE, 3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one,1,7-DIHYDRO- 4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE, 1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
I-CAS RN: 3680-71-5
I-Molecular Formula: C6H5N3O
Isisindo samangqamuzana: 135.12 >
Ifomula Yesakhiwo:

I-EINECS NO.: 640-613-6

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Impahla

Iphuzu elincibilikayo: 345-348°C
Indawo yokubilisa: 473.1±18.0 °C(Kubikezelwe)
Ukuminyana: 1.62± 0.1g /cm3(Kubikezelwe)
I-RTECS: UY9440000
Izimo zesitoreji ngu-2-8°C
Ukunyibilika: Kuncibilika ku-dimethyl sulfoxide.
Ifomu: Okuqinile
I-acidity coefficient (pKa) 11.99 + 0.20 (Kubikezelwe)
Ukuzwela: Umswakama & Okunsundu Okukhanyayo
InChIKeyFBMZEITWVNHWJW UHFFFAOYSA - N

Ulwazi lokuphepha

Uphawu lwengozi (GHS):

Igama lesixwayiso: Isexwayiso
Incazelo yengozi: H317-H319
Izinyathelo zokuphepha: P280-P302+P352-P305+P351+P338
Ikhodi Yekilasi Lengozi: 36-43
Imiyalo yokuphepha: 26-36/37
I-WGK Germany : 3
Inothi Lengozi :Iyacasula
Ikhodi ye-HS: 29335990

Imibandela yokugcina okuphephile, okuhlanganisa noma yikuphi ukungahambisani

Gcina endaweni epholile. Gcina isitsha sivaliwe futhi ugcine endaweni eyomile, engenawo umoya.
Izinga lokushisa elinconyiwe lesitoreji: 2-8 °C
Sebenza ngaphansi kwe-nitrogen ukuze ugweme umswakama. Izwela ukushisa, ukukhanya kanye nomswakama ogcinwe ku-nitrogen.

Iphakheji

Ipakishwe ku-25kg/drum, ifakwe isikhwama sepulasitiki esiphindwe kabili, noma ipakishwe ngokwezidingo zamakhasimende.

Izinkambu Zokusebenza

Okuphakathi, Pharmaceutical Intermediate
Kuyi-prodrug ye-xanthine oxidase ecushiwe i-thymidine phosphorylase inhibitors.
Kuyi-organic synthesis kanye ne-Pharmaceutical Intermediate, ikakhulukazi esetshenziswa ekukhiqizeni i-tofacitinib, i-barricitinib nezinye izidakamizwa ezilwa nomdlavuza ohlelweni lokuhlanganisa amakhemikhali nemithi.

imininingwane yemikhiqizo

Isimo Sesitoreji
Gcina esitsheni esingangenisi umoya ekamelweni lokushisa.

Iphakheji
Ipakishwe ku-25kg/drum, ifakwe isikhwama sepulasitiki esiphindwe kabili, noma ipakishwe ngokwezidingo zamakhasimende.

Izinkambu Zokusebenza
Okuphakathi, Pharmaceutical Intermediate

Ukucaciswa Kwekhwalithi

INTO YOKUHLOLA	INKCAZO
Izici	Okuqinile okumhlophe kuya kokumhlophe
Okuqukethwe Amanzi	≤0.5%
Ubumsulwa(nge-HPLC)	≥98.0%
I-Assay(nge-HPLC)	≥98.0%

Imikhiqizo ekhuphukayo

INOMBOLO YE-CAS: 67831-84-9
Igama lomkhiqizo: 4H-Pyrrolo[2,3-d]pyrimidin-4-one,1,2,3,7-tetrahydro-2-thioxo-
Ifomula yemolekyuli: C6H5N3OS

INOMBOLO YECAS:7400-06-8
Igama lomkhiqizo: 6-Amino-5-(2,2-diethoxyethyl)pyrimidin-4-ol
Ifomula yemolekyuli:C10H17N3O3

INOMBOLO YECAS.:56-86-0
Igama lomkhiqizo: L-glutamic acid
Ifomula yemolekyuli:C5H9NO4

Inombolo ye-CAS: 52133-67-2
Igama Lomkhiqizo: Ethyl 2-cyano-4,4-diethoxybutyrate
Ifomula yemolekyuli: C11H19NO4

Inombolo ye-CAS: 7400-05-7
Igama Lomkhiqizo:4(1H)-Pyrimidinone,6-amino-5-(2,2-diethoxyethyl)-2,3-dihydro-2-thioxo-
Ifomula yemolekyuli:C10H17N3O3S

Imikhiqizo esakazwa phansi

Inombolo ye-CAS: 3680-69-1
Igama Lomkhiqizo:4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Ifomula yemolekyuli:C6H4ClN3

Inombolo ye-CAS: 346599-63-1
Igama lomkhiqizo: 4-Chloro-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one
Ifomula yemolekyuli:C6H4ClN3O

Inombolo ye-CAS: 941685-26-3
Igama Lomkhiqizo:4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine
Ifomula yemolekyuli:C12H18ClN3OSi