Ukuqonda ukusetshenziswa kwe-5-isosorbide monitrate

I-5-isosorbide monitrate (ismn) umuthi osungulwe kahle osetshenziswa ekwelapheni izimo ezahlukahlukene zenhliziyo. Le mpikiswano iyingxenye yezigaba ze-nitrate yezidakamizwa, ezaziwa ngekhono lazo lokuthuthukisa ukugeleza kwegazi futhi kudambise izimpawu zesifo senhliziyo. Uma ubekelwe lo muthi noma ubheka izinzuzo zawo ezingaba khona, ukuqonda ukusetshenziswa kwalo nokuthi kusebenza kanjani kubalulekile. Kulesi sihloko, sizohlola okuyisisekeloI-5-isosorbide mononitrate isebenzisanokuthi kusiza kanjani ukuphatha izimo zenhliziyo ngempumelelo.

Yini i-5-isosorbide donitrate?

I-5-isosorbide monitrateUmuthi we-nitrate usebenza ngokuyinhloko njenge-vasodilator, okusho ukuthi kuyasiza ukunweba imithambo yegazi. Lokhu kuphumela ekuhambeni kwegazi okuthuthukile futhi kunciphise ubunzima enhliziyweni. Imvamisa ebekelwe iziguli ezine-angina (izinhlungu zesifuba) noma ukwehluleka kwenhliziyo, kanye nalabo abahlinza inhliziyo. I-5-isosorbide comonitrate iyatholakala kuzo zombili izindlela zokukhishwa ngokushesha nokukhishwa okunwetshiwe, okunikeza ukuguquguquka ekuphatheni izinhlobo ezahlukene zezimo zenhliziyo.

Ukusetshenziswa Okusemqoka kwe-5-isosorbide monitrate

1. Ukuphatha i-angina

Enye yezinto ezivame kakhuluI-5-isosorbide mononitrate isebenzisaekuphathweni kwe-angina. U-Angina ubuhlungu besifuba noma ukungakhululeki okubangelwa ukugeleza kwegazi okuncishisiwe emsipha wenhliziyo, kuvame ngenxa yesifo se-artery se-coronary. Ngokuphumula kwemithambo yegazi kanye nokwenza ngcono ukujikeleza kwegazi, i-5-isosorbide connitrate kusiza ukukhulisa inani legazi elicebile emoyeni elifinyelela enhliziyweni, elinganciphisa kakhulu imvamisa nobunzima bokuhlaselwa kwe-angina.

Lo muthi uvame ukunqunywa njengengxenye yohlelo lokuthola ukwelashwa olubanzi, olungafaka neminye imithi, izinguquko zendlela yokuphila, futhi ngezinye izikhathi ukungenelela okuvivinyayo.

2. Ukuphatha Ukwehluleka Kwenhliziyo

Okunye ukusetshenziswa okubalulekile kwe-5-isosorbide monitrate kusekuphaneni ukwehluleka kwenhliziyo. Ekwehluleka kwenhliziyo, inhliziyo iba yimpumelelo ekumpompeni igazi, okuholela ekwakheni uketshezi nokwehla kokulethwa komoya-mpilo ezithweni ezibalulekile. Umphumela we-vasodilatory we-5-isosorbide Monitrate kusiza ukunciphisa umthwalo wenhliziyo enhliziyweni ngokunciphisa ingcindezi emithanjeni yegazi, okwenza kube lula ukuthi izinhliziyo zimpompe.

Ngokwenza ngcono ukugeleza kwegazi futhi kunciphisa ingcindezi enhliziyweni, i-5-isosorbide Monitrate isiza ukuvimbela ukuqhubekela phambili kwenhliziyo yokwehluleka futhi kuthuthukise ikhwalithi yempilo yesiguli. Lokhu kusiza ikakhulukazi kubantu abanokuhluleka kwenhliziyo okudinga ukuphathwa isikhathi eside ukuvikela ukwanda.

3. Ukuvimbela nokwelapha i-Ischemia

I-Ischemia yenzeka lapho igazi lifaka enhliziyweni noma kwezinye izingxenye zomzimba alwanele ukufeza izimfuno zezicubu. Lesi simo singaholela ekulimaleni kwemisipha yenhliziyo futhi sandise ubungozi bokuhlaselwa yinhliziyo. I-5-Isasorbide Monitrate kwesinye isikhathi isetshenziswa ezigulini ezine-Ischemic Heart Diseef ukuvikela ukwenzeka kwe-Ischemia futhi kunciphise ubungozi bokulimala kwenhliziyo okuqhubekayo.

Ngokwandisa imithambo yegazi kanye nokwenza ngcono ukujikeleza kwegazi, i-5-isosorbide monitonitrate iqinisekisa ukuthi umoya-mpilo owanele ufinyelela imisipha yenhliziyo, noma ngabe ukugeleza kwegazi kuncipha. Lokhu kusiza ukuvikela inhliziyo emonakalweni ngenxa ye-Ischemia, okwenza kube nemithi ebalulekile yeziguli ezisengozini.

4. Ukuvuselela ngemuva kokuhlinzwa

Iziguli ezihlinzwe yinhliziyo, njenge-coronary artery bypass ngokuxhunyelelwa (i-CABG), nazo zingazuza kuma-moninline ayi-5-isoosorbide. Ngemuva kokuhlinzwa, inhliziyo ingaba ngaphansi kwengcindezi eyandayo njengoba ipholisa, futhi iziguli zingathola izinhlungu esifubeni noma ukungaphatheki kahle ngesikhathi sokubuyisa. I-vasodilation enikezwe i-donitrate engu-5-isosorbide ingadambisa umthwalo enhliziyweni ngalesi sikhathi esibucayi, ivumela ukululama okungcono futhi kuncishiswe ubungozi bezinkinga.

Ngabe isebenza kanjani ama-5-isosorbide monitrate?

I-5-isosorbide comonitrate isebenza ngokuphumula izicubu ezibushelelezi zemithambo yegazi. Lokhu kuphumela eVasodilation, okuwukunwetshwa kwemithambo yegazi. Inzuzo eyinhloko yalomphumela ukuthi yehlisa inani lomsebenzi inhliziyo okufanele yenziwe ukupompa ukupompa igazi, ukunciphisa ukusetshenziswa komoya-mpilo kwenhliziyo kanye nomfutho wegazi ngaphakathi kwemikhumbi.

Ngokuphumula nokwandisa imithambo yegazi, ama-moninate ama-isasorbide athuthukisa ukuhamba kwegazi, okuzuzisa kakhulu ngabantu abanezimo zenhliziyo lapho ukusakazwa kwehlekwe khona. Umuthi obekezelelwa kahle okuvame ukubekwa njengengxenye yohlelo lokwelashwa olubanzi lokuphatha isifo senhliziyo.

Imiphumela emibi engaba khona kanye nokucatshangelwa

Ngenkathi i-5-isosorbide monitrate ivame ukubekezelelwa kahle, kubalulekile ukuthi wazi imiphumela emibi engaba khona. Lokhu kungafaka amakhanda, isiyezi, umfutho wegazi ophansi, ne-nausea. Kwezinye izimo, ukubekezelela kungakhulisa, okusho ukuthi ukusebenza kwemithi kungancipha ngokuhamba kwesikhathi. Kubalulekile ukulandela imiyalo yakho yomhlinzeki wezokunakekelwa kwezempilo maqondana nomthamo kanye nemvamisa ukugwema noma yiziphi izinkinga.

Njenganoma imuphi umuthi, kubalulekile ukudingida umlando wakho wezokwelapha nodokotela wakho, ikakhulukazi uma unezimo ezifana ne-hypotension noma umlando wokuhlaselwa yinhliziyo. Umhlinzeki wakho wezokunakekelwa kwempilo angasiza ekuboneni ukuthi i-5-isosorbide monitrate ingukukhetha okulungile kwesimo sakho esithile.

Isiphetho: Ukuphatha Izimo Zenhliziyo Ngokuphumelelayo

Le khasiI-5-isosorbide mononitrate isebenzisaKuchazwe lapha Khombisa ukuthi le mithi idlala kanjani indima ebalulekile ekuphathweni kwezimo zenhliziyo, ukusuka ekunciphiseni i-angina futhi ivikele i-Ischemia ukusekela ukwelashwa kwenhliziyo nokusiza ukululama ngemuva kokuhlinzwa. Ngokwenza ngcono ukugeleza kwegazi futhi kunciphisa umthwalo wenhliziyo enhliziyweni, i-5-isosorbide Monitrate isiza ukuthuthukisa ikhwalithi yempilo yabantu abaningi ngesifo senhliziyo.

Uma wena noma umuntu omaziyo ubhekene nezimo zenhliziyo, kubalulekile ukubheka nomhlinzeki wezokunakekelwa kwempilo ukuthola ukuthi ngabe i-5-isosorbide donitrate ingaba yingxenye yohlelo lokwelashwa olusebenzayo. E-New venture, sizibophezele ekuhlinzekeni izixazululo zezempilo ezisezingeni eliphakeme zemikhakha ehlukahlukene. Xhumana nathi namuhla ukuze ufunde kabanzi ngeminikelo yethu nokuthi singazisekela kanjani izidingo zakho zezempilo.