I-C11H15N5O5 Guanosine, 2′ -O-methyl- (7CI, 8CI, 9CI, ACI)

umkhiqizo

I-C11H15N5O5 Guanosine, 2′ -O-methyl- (7CI, 8CI, 9CI, ACI)

Ulwazi Oluyisisekelo:


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Imininingwane Yezidakamizwa

Inombolo Yokubhalisa ye-CAS

2140-71-8

Izici Zomzimba Eziyinhloko Inani Isimo
Isisindo samangqamuzana 297.27 -
I-Melting Point (Eyokuhlola) 233-235 °C I-solvent: I-Methanol
Ukuminyana (Kubikezelwe) 1.98±0.1 g/cm3 Izinga lokushisa: 20 °C; Cindezela: 760 Torr
pKa (Kubikezelwe) 9.64±0.20 Izinga Le-Acidic Elikhulu: 25 °C

Amanye Amagama Nezihlonzi

I-Canonical SMILES

O=C1N=C(N)NC2=C1N=CN2C3OC(CO)C(O)C3OC

I-Isomeric SMILES

O(C)[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](CO)[C@H ]1O

I-InChI

I-InChI= 1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9( 5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19) /t4-,6-,7-,10-/m1/s1

Ukhiye we-InchI

I-OVYNGSFVYRPRCG-KQYNXXCUSA-N

1 Elinye Igama lale nto

2′-O-Methylguanosine (ACI)

Izakhiwo ezitholakalayo
Amakhemikhali
Okushisayo

Amakhemikhali

Impahla Isimo Sevalue Umthombo
pKa 9.5 (1) I-CAS

(1) Bhamra, Inder; Ucwaningo lwe-Nucleic Acids,

Okushisayo

Impahla Inani Isimo Umthombo
I-Melting Point 233-235 °C I-solvent: I-Methanol (1) I-CAS

(1) Kore, Anilkumar R.; Ama-Nucleosides, ama-Nucleotides nama-Nucleic Acids,

I-Spectra yokuhlola

I-Spectra iyatholakala
1 H NMR
13 C NMR
IMisa

Izakhiwo Ezibikezelwe

Izakhiwo ezitholakalayo
I-Biological
Amakhemikhali
Ukuminyana
Lipinski
Okuhlobene Nesakhiwo

I-Biological

Impahla Inani Isimo Umthombo
I-Bioconcentration Factor 1.0 i-pH 1; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 pH 2; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 i-pH 3; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 i-pH 4; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 pH 5; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 pH 6; Izinga lokushisa: 25 °C (1) ACD

 

Impahla Inani Isimo Umthombo
I-Bioconcentration Factor 1.0 pH 7; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 pH 8; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 pH 9; Izinga lokushisa: 25 °C (1) ACD
I-Bioconcentration Factor 1.0 pH 10; Izinga lokushisa: 25 °C (1) ACD

(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Amakhemikhali

Impahla Inani Isimo Umthombo
Koc 1.0 i-pH 1; Izinga lokushisa: 25 °C (1) ACD
Koc 1.19 pH 2; Izinga lokushisa: 25 °C (1) ACD
Koc 3.42 i-pH 3; Izinga lokushisa: 25 °C (1) ACD
Koc 4.23 i-pH 4; Izinga lokushisa: 25 °C (1) ACD
Koc 4.33 pH 5; Izinga lokushisa: 25 °C (1) ACD
Koc 4.34 pH 6; Izinga lokushisa: 25 °C (1) ACD
Koc 4.33 pH 7; Izinga lokushisa: 25 °C (1) ACD
Koc 4.24 pH 8; Izinga lokushisa: 25 °C (1) ACD
Koc 3.48 pH 9; Izinga lokushisa: 25 °C (1) ACD
Koc 1.28 pH 10; Izinga lokushisa: 25 °C (1) ACD
logD -2.76 i-pH 1; Izinga lokushisa: 25 °C (1) ACD
logD -1.92 pH 2; Izinga lokushisa: 25 °C (1) ACD
logD -1.46 i-pH 3; Izinga lokushisa: 25 °C (1) ACD
logD -1.37 i-pH 4; Izinga lokushisa: 25 °C (1) ACD
logD -1.36 pH 5; Izinga lokushisa: 25 °C (1) ACD
logD -1.36 pH 6; Izinga lokushisa: 25 °C (1) ACD
logD -1.36 pH 7; Izinga lokushisa: 25 °C (1) ACD
logD -1.37 pH 8; Izinga lokushisa: 25 °C (1) ACD
logD -1.45 pH 9; Izinga lokushisa: 25 °C (1) ACD
logD -1.89 pH 10; Izinga lokushisa: 25 °C (1) ACD
logP -1.359±0.544 Izinga lokushisa: 25 °C (1) ACD
I-Mass Intrinsic Solubility 1.1 g/L Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 27 g/L i-pH 1; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 3.9 g/L pH 2; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.4 g/L i-pH 3; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.1 g/L i-pH 4; Izinga lokushisa: 25 °C (1) ACD

 

Impahla Inani Isimo Umthombo
I-Mass Solubility 1.1 g/L pH 5; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.1 g/L pH 6; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.1 g/L pH 7; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.1 g/L pH 8; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.3 g/L pH 9; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 3.6 g/L pH 10; Izinga lokushisa: 25 °C (1) ACD
I-Mass Solubility 1.1 g/L Amanzi Angakhiqiziwe pH 6.17; Izinga lokushisa: 25 °C (1) ACD
I-Molar Intrinsic Solubility 3.6 x 10-3 mol/L Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 0.091 mol/L i-pH 1; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 0.013 mol/L pH 2; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 4.6 x 10-3 mol/L i-pH 3; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 3.7 x 10-3 mol/L i-pH 4; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 3.7 x 10-3 mol/L pH 5; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 3.6 x 10-3 mol/L pH 6; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 3.7 x 10-3 mol/L pH 7; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 3.7 x 10-3 mol/L pH 8; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 4.5 x 10-3 mol/L pH 9; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 0.012 mol/L pH 10; Izinga lokushisa: 25 °C (1) ACD
I-Molar Solubility 3.6 x 10-3 mol/L Amanzi Angakhiqiziwe pH 6.17; Izinga lokushisa: 25 °C (1) ACD
Isisindo samangqamuzana 297.27    
pKa 9.64±0.20 Izinga Le-Acidic Elikhulu: 25 °C (1) ACD
pKa 2.42±0.10 Izinga Lokushisa Eziyisisekelo: 25 °C (1) ACD

(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Ukuminyana

Impahla Inani Isimo Umthombo
Ukuminyana 1.98±0.1 g/cm3 Izinga lokushisa: 20 °C; Cindezela: 760 Torr (1) ACD
Ivolumu ye-Molar 149.8±7.0 cm3/mol Izinga lokushisa: 20 °C; Cindezela: 760 Torr (1) ACD

(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Lipinski

Impahla Inani Umthombo Wesimo
Amabhondi Ashintshashintshayo Ngokukhululekile 5 (1) ACD

 

Impahla Inani Isimo Umthombo
H Abamukelayo 10   (1) ACD
H Abanikeli 5   (1) ACD
H Isamba Somnikeli/Umamukeli 15   (1) ACD
logP -1.359±0.544 Izinga lokushisa: 25 °C (1) ACD
Isisindo samangqamuzana 297.27    

(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Okuhlobene Nesakhiwo

Impahla Inani Umthombo Wesimo
Indawo ye-Polar Surface 144 A2 (1) ACD

(1) Kubalwe kusetshenziswa i-Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

I-Spectra ebikezelwe

I-Spectra iyatholakala
1 H NMR
13 C NMR


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