I-2-hydroxypyridine-N-oxide (HOPO)

Ulwazi Oluyisisekelo:

Igama lekhemikhali: 2-hydroxypyridine-n-oxide;

Inombolo ye-CAS: 13161-30-3

Ifomula yemolekyuli: C5H5NO2

Isisindo se-molecule: 111.1

Inombolo ye-EINECS: 236-100-88

Ifomula yesakhiwo:

Izigaba ezihlobene: Abaphakathi kwezemithi; I-polypeptide reagent - ingxube ye-shrinkage; Organic chemical izinto zokusetshenziswa.

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Impahla ye-Physicochemical

Indawo yokuncibilika: 147-152 °C

Indawo yokubilisa: 387.7±15.0 °C(Kubikezelwe)

Ukuminyana: 1.111 Iphoyinti elikhanyayo: 100 °C

Inkomba ye-refractive: 1.554

Ukucindezela komhwamuko: 0.223Pa ku-25 °C

Ukunyibilika: kuncibilika kancane ku-chloroform, i-DMSO, i-methanol, amanzi.

Izakhiwo: Impushana ephuzi ukuya kokukhanyayo.

LogP: -1.07at 25℃

Inkomba yokucaciswa

Sukucaciswa	Unithi	Sejwayelekile
Ukubukeka		Impushana ephuzi kuya kokuphuzi
Ukulahlekelwa ekomisweni	%	≤0.5
Iphoyinti lokuncibilika	℃	149-152

Isicelo somkhiqizo

Ingasetshenziswa njenge-ejenti yokunciphisa, i-catalyst kanye ne-ejenti eyisizayo. Ku-peptide synthesis, ukungezwa kwezinsiza zokufingqa kungasheshisa isivinini sokusabela futhi kunciphise ukugijima kwe-racemization, ukuze kuvale ukushoda kwama-reagents e-condensation. I-HOPO iyinhlobonhlobo yezinsiza ezinjalo zokufingqa. I-2-hydroxypyridine-n-oxide iyinhlanganisela ebalulekile. Ucwaningo lwakamuva luye lwathola ukuthi le nhlanganisela inendima ekhethekile ekuvimbeleni ukuwohloka kwezinkuni ngenxa ye-white-rotfungi. Ngesikhathi esifanayo, iyi-ejenti entsha nesebenzayo ye-subway chelating. I-complex eyakhiwe yi-compound kanye ne-vanadium nayo idlala indima ebalulekile ku-biochemistry.