![C50H60N5O10P Cytidine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O- (2-methoxyethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis (1-methylethyl) phosphoramidite] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C50H60N5O10P Cytidine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O- (2-methoxyethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis (1-methylethyl) phosphoramidite] (ACI) Chithunzi Chowonetsedwa](https://www.csnvchem.com/uploads/C50H60N5O10P-Cytidine.png)
C50H60N5O10P Cytidine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O- (2-methoxyethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis (1-methylethyl) phosphoramidite] (ACI)
Nambala ya Registry ya CAS
163759-94-2
| Zofunika Zathupi | Mtengo | Mkhalidwe |
| Kulemera kwa Maselo | 922.01 | - |
| pKa (Zonenedweratu) | 8.59±0.40 | Kutentha Kwambiri kwa Acid: 25 ° C |
Canonical SMILES
N#CCCOP(OC1C(OC(N2C=C(C(= NC2=O)NC(=O)C=3C=CC=CC3)C)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC =C(OC)C=C5)C6=CC=C(OC)C=C 6)N(C(C)C)C(C)C
Isomeric AMAmwetulira
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@ H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC =C(OC)C=C4)(C5= CC=C(OC)C=C5)C6=CC=CC=C6
InChi
InChI= 1S/C50H60N5O10P/c1-34(2)55(35(3)4)66(63-29-15-28-51)65-44-43(33-62-50(38-18-13-) 10-14-19-38,39-20-24-41(59-7)25-21-39 )40-22-26-42(60-8)27-23-40)64-48(45( 44)61-31-30-58-6)54-32-36(5)46(53-49(54)57)52-47(56)37-16-11-9-12-17-37/ h9-14,16-27,32,34- 35,43-45,48H,15,29-31,33H2,1-8H3,(H,52,53,56,57)/t43-,44-, 45-,48-,66?/m1/s1
InChi Key
FIGVMLIIDVDSN-GICDFOIUSA-N
26 Maina ena a chinthu ichi
Cytidine,N-benzoyl-5'-O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methoxyethyl)- 5-methyl-, 3′ - [2-cyanoethyl bis(1-methylethyl) phosphoramidite] (9CI); 12: PN: WO03084478 TSAMBA: 57 amati DNA; 14: PN: US20030170636 TSAMBA: 17 amati DNA; 15: PN: U
S20030211606 TSAMBA: 19 amati DNA; 15: PN: US20030212017 TSAMBA: 19 amati DNA; 16: PN: US20040005569 TSAMBA: 22 amati DNA; 17: PN: US20040006030 TSAMBA: 23 amati DNA; 17: PN: US20040014049 TSAMBA: 20 amati DNA; 18: PN: US20040014047 PAG E: 20 amati DNA; 18: PN: US20040014048 TSAMBA: 20 amati DNA; 18: PN: US20040014050 TSAMBA: 20 amati DNA; 19: PN: U
S20030171313 TSAMBA: 9 amati DNA; 19: PN: US20030198965 TSAMBA: 20 amati DNA; 19: PN: US20040005565 TSAMBA: 17- 22 amati DNA; 19: PN: US20040005570 TSAMBA: 20 amati DNA; 19: PN: US20040014051 TSAMBA: 22 amati DNA; 20: PN: US20040014699 PAG
E: 20 amati DNA; 21: PN: US20040006029 TSAMBA: 23 amati DNA; 21: PN: WO03106645 TSAMBA: 72 amati DNA; 61: PN: US20030
166592 TSAMBA: 15 amati DNA; 7: PN: WO2005006958 TSAMBA: 62 amati DNA; 84: PN: US20040171566 TSAMBA: 18 amati DNA; 92:
PN: US20040005707 TSAMBA: 20 amati DNA; 9: PN: WO2005007825 TSAMBA: 62 amati DNA;N4-Benzoyl-2'-Omethoxyethyl-5-Odimethoxytrityl-5-methylcytidine-3'-phosphoramidite;N4-Benzoyl-2'-O- methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine-3' - amidite
Spectra ilipo
13 C NMR
Hetero NMR
Katundu zilipo
Zachilengedwe
Chemical
Lipinski
Zogwirizana ndi Kapangidwe
| Katundu | Mtengo | Mkhalidwe | Gwero |
| Bioconcentration Factor | 171 | pH 1; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 1250 | pH 2; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 47600 | pH 3; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 6.44x105 | pH 4; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 1.00x106 | pH 5; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 1.00x106 | pH 6; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 1.00x106 | pH 7; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 7.79 x 105 | pH 8; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 1.63x105 | pH 9; Kutentha: 25 ° C | (1) ACD |
| Bioconcentration Factor | 30800 | pH 10; Kutentha: 25 ° C | (1) ACD |
(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Katundu | Mtengo | Mkhalidwe | Gwero |
| Koc | 106 | pH 1; Kutentha: 25 ° C | (1) ACD |
| Koc | 773 | pH 2; Kutentha: 25 ° C | (1) ACD |
| Koc | 29500 | pH 3; Kutentha: 25 ° C | (1) ACD |
| Katundu | Mtengo | Mkhalidwe | Gwero |
| Koc | 3.99 x 105 | pH 4; Kutentha: 25 ° C | (1) ACD |
| Koc | 8.02 x 105 | pH 5; Kutentha: 25 ° C | (1) ACD |
| Koc | 8.70 x 105 | pH 6; Kutentha: 25 ° C | (1) ACD |
| Koc | 8.16 x 105 | pH 7; Kutentha: 25 ° C | (1) ACD |
| Koc | 4.83 x 105 | pH 8; Kutentha: 25 ° C | (1) ACD |
| Koc | 1.01x105 | pH 9; Kutentha: 25 ° C | (1) ACD |
| Koc | 19100 | pH 10; Kutentha: 25 ° C | (1) ACD |
| logD | 4.48 | pH 1; Kutentha: 25 ° C | (1) ACD |
| logD | 5.34 | pH 2; Kutentha: 25 ° C | (1) ACD |
| logD | 6.92 | pH 3; Kutentha: 25 ° C | (1) ACD |
| logD | 8.06 | pH 4; Kutentha: 25 ° C | (1) ACD |
| logD | 8.36 | pH 5; Kutentha: 25 ° C | (1) ACD |
| logD | 8.39 | pH 6; Kutentha: 25 ° C | (1) ACD |
| logD | 8.37 | pH 7; Kutentha: 25 ° C | (1) ACD |
| logD | 8.14 | pH 8; Kutentha: 25 ° C | (1) ACD |
| logD | 7.46 | pH 9; Kutentha: 25 ° C | (1) ACD |
| logD | 6.73 | pH 10; Kutentha: 25 ° C | (1) ACD |
| logP | 8.401±0.723 | Kutentha: 25 ° C | (1) ACD |
| Mass Intrinsic Solubility | 1.4 x 10-4 g/L | Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 1.1g/L | pH 1; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 0.16g/L | pH 2; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 4.1 x 10-3 g/L | pH 3; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 3.0 x 10-4 g/L | pH 4; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 1.5 x 10-4 g/L | pH 5; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 1.4 x 10-4 g/L | pH 6; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 1.5 x 10-4 g/L | pH 7; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 2.5 x 10-4 g/L | pH 8; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 1.2 x 10-3 g/L | pH 9; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 6.3 x 10-3 g/L | pH 10; Kutentha: 25 ° C | (1) ACD |
| Misa Solubility | 1.5 x 10-4 g/L | Madzi Osasunthika pH 6.97; Kutentha: 25 ° C | (1) ACD |
| Molar Intrinsic Solubility | 1.5 x 10-7 mol / L | Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 1.2 x 10-3 mol / L | pH 1; Kutentha: 25 ° C | (1) ACD |
| Katundu | Mtengo | Mkhalidwe | Gwero |
| Molar Solubility | 1.7 x 10-4 mol / L | pH 2; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 4.4 x 10-6 mol / L | pH 3; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 3.2 x 10-7 mol / L | pH 4; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 1.6 x 10-7 mol / L | pH 5; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 1.5 x 10-7 mol / L | pH 6; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 1.6 x 10-7 mol / L | pH 7; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 2.7 x 10-7 mol / L | pH 8; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 1.3 x 10-6 mol / L | pH 9; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 6.8 x 10-6 mol / L | pH 10; Kutentha: 25 ° C | (1) ACD |
| Molar Solubility | 1.6 x 10-7 mol / L | Madzi Osasunthika pH 6.97; Kutentha: 25 ° C | (1) ACD |
| Kulemera kwa Maselo | 922.01 | ||
| pKa | 8.59±0.40 | Kutentha Kwambiri kwa Acid: 25 ° C | (1) ACD |
| pKa | 3.87±0.20 | Kutentha Kwambiri Kwambiri: 25 °C | (1) ACD |
(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Katundu | Mtengo | Mkhalidwe | Gwero |
| Ma Bond Osinthasintha Mwaulere | 22 | (1) ACD | |
| H Olandira | 15 | (1) ACD | |
| H Opereka | 1 | (1) ACD | |
| H Chiwerengero cha Wopereka / Wolandira | 16 | (1) ACD | |
| logP | 8.401±0.723 | Kutentha: 25 ° C | (1) ACD |
| Kulemera kwa Maselo | 922.01 |
(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Katundu | Mtengo | Condition Source |
| Malo a Polar Surface | 176 a2 | (1) ACD |
(1) Owerengedwa pogwiritsa ntchito Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Spectra ilipo
1H NMR
13 C NMR
![C48H54N7O8P Adenosine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – O-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphor amidite] (ACI)](https://www.csnvchem.com/uploads/C48H54N7O8P-300x300.png)
![C41H49FN5O8P Cytidine, N-acetyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – deoxy-2′ -fluoro-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl) phosphor amidite] (ACI)](https://www.csnvchem.com/uploads/C41H49FN5O8P-Cytidine-300x300.png)
![C40H49N4O9P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-methyl-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] (ACI)](https://www.csnvchem.com/uploads/C40H49N4O9P-Uridine-300x300.png)
![C44H53FN7O8 Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -deoxy-2′ – fluoro-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N, N-bis(1-methyl ethyl)phosphoramidite] (ACI)](https://www.csnvchem.com/uploads/C44H53FN7O8-300x300.png)
![C47H60N7O10P Guanosine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2- methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′ – [2-cyanoethyl N N-bis (1-methylethyl)phosphoramidite] (ACI)](https://www.csnvchem.com/uploads/C47H60N7O10P-Guanosine-300x300.png)
![C47H51FN7O7P Adenosine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – deoxy-2′ -fluoro-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl) phosphor amidite] (ACI)](https://www.csnvchem.com/uploads/C47H51FN7O7P-Adenosine-300x300.png)