C43H55N4O10P Uridine, 5'-O- [bis (4-methoxyphenyl) phenylmethyl] -2'-O- (2-methox yethyl) - 5-methyl-, 3'- [2-cyanoethyl N, N-bis (1-) methylethyl phosphor amidite (ACI)

samfur

C43H55N4O10P Uridine, 5'-O- [bis (4-methoxyphenyl) phenylmethyl] -2'-O- (2-methox yethyl) - 5-methyl-, 3'- [2-cyanoethyl N, N-bis (1-) methylethyl phosphor amidite (ACI)

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Cikakken Bayani

Tags samfurin

Bayanin Abu

Lambar Rijistar CAS

163878-63-5

H302

Mabuɗin Abubuwan Jiki Daraja Yanayi
Nauyin Kwayoyin Halitta 818.89 -
pKa (An annabta) 9.55± 0.10 Mafi yawan zafin jiki: 25 ° C

Sauran Sunaye da Masu Ganewa

MURMUSHI na Canonical

N#CCCOP(OC1C(OC(N2C=C(C(=O)) NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5= CC=C(OC)C=C5)N(C(C)C)C(C)C

MURMUSHI

C(OC[C@H] 1[C@@H](OP(N(C)C)C(C)C)OCCC#N H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC) =C(OC)C=C4)C5=CC=CC=C5

InChi

InChi= 1S/C43H55N4O10P/c1-29(2)47(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26-25- 50-6) 46-27-31 (5)40 (48) 45-42 (46)49)2 8-54-43 (32-13-10-9-11-14-32,33-15-19-35(51-7)20-16-33)34-17-21 -36 (52-8)22-18-34/h9-11,13-22,27,29-30,37-39,41H,12,24-26,28H2, 1-8H3,(H,45,48,49)/t37-,38-,39-,41-,58?/m1/s1

InChi Key

YFRRKZDUDXHJNC-KZQAAKLLSA-N

Wasu Sunaye 17 na wannan Abu

Uridine, 5'-O- [bis (4-methoxyphenyl) phenylmethyl]-2′-O(2-methoxyethyl) - 5-methyl-, 3′- [2-cyanoethyl bis (1-methylethyl) phosphore

amidite] (9CI); 10: PN: US20030212017 SHAFI: 18 da'awar RNA; 11: PN: US20030211606 SHAFI: 18 da'awar RNA; 13: PN: US20040

005569 SHAFI: 21 da'awar RNA; 13: PN: US20040006030 SHAFI: 22 da'awar RNA; 13: PN: US20040014048 SHAFI: 19 da'awar RNA; 13: PN: US20040014049 SHAFI: 19 da'awar RNA; 14: PN: US20030198965 SHAFI: 19 da'awar RNA; 14: PN: US20040005565 SHAFI: 17- 22 da'awar RNA; 14: PN: US20040005570 SHAFI: 19 da'awar RNA; 14: PN: US20040014047 SHAFI: 19 da'awar RNA; 14: PN: US20040

014699 SHAFI: 19 da'awar RNA; 15: PN: US20040014050 SHAFI: 19 da'awar RNA; 15: PN: US20040014051 SHAFI: 21 da'awar RNA; 15:

PN: WO03106645 SHAFI: 69 da'awar RNA; 16: PN: US20040006029 SHAFI: 22 da'awar RNA; 87: PN: US20040005707 SHAFI: 19 da'awar RNA

Spectra na Gwaji

Spectra akwai
1 H NMR
13 C NMR
Farashin NMR

Kayayyakin Hasashen

Properties akwai
Halittu
Chemical
Lipinski
Tsarin Yanayi

Halittu

Dukiya Daraja Yanayi Source
Factor na Bioconcentration 348 pH da 1; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 2810 pH da 2; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 21100 pH da 3; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 63100 pH da 4; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 78800 pH da 5; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 80800 pH da 6; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 80800 pH da 7; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 78800 pH da 8; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 63400 pH da 9; Zazzabi: 25 ° C (1) ACD
Factor na Bioconcentration 21800 pH 10; Zazzabi: 25 ° C (1) ACD

(1) An ƙididdige ta ta amfani da Ci gaban Chemistry na Babba (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Chemical

Dukiya Daraja Yanayi Source
Koc 487 pH da 1; Zazzabi: 25 ° C (1) ACD
Koc 3940 pH da 2; Zazzabi: 25 ° C (1) ACD
Koc 29600 pH da 3; Zazzabi: 25 ° C (1) ACD
Koc 88400 pH da 4; Zazzabi: 25 ° C (1) ACD

 

Dukiya Daraja Yanayi Source
Koc 1.10 x 105 pH da 5; Zazzabi: 25 ° C (1) ACD
Koc 1.13 x 105 pH da 6; Zazzabi: 25 ° C (1) ACD
Koc 1.13 x 105 pH da 7; Zazzabi: 25 ° C (1) ACD
Koc 1.10 x 105 pH da 8; Zazzabi: 25 ° C (1) ACD
Koc 88800 pH da 9; Zazzabi: 25 ° C (1) ACD
Koc 30600 pH 10; Zazzabi: 25 ° C (1) ACD
logD 4.39 pH da 1; Zazzabi: 25 ° C (1) ACD
logD 5.30 pH da 2; Zazzabi: 25 ° C (1) ACD
logD 6.18 pH da 3; Zazzabi: 25 ° C (1) ACD
logD 6.65 pH da 4; Zazzabi: 25 ° C (1) ACD
logD 6.75 pH da 5; Zazzabi: 25 ° C (1) ACD
logD 6.76 pH da 6; Zazzabi: 25 ° C (1) ACD
logD 6.76 pH da 7; Zazzabi: 25 ° C (1) ACD
logD 6.75 pH da 8; Zazzabi: 25 ° C (1) ACD
logD 6.65 pH da 9; Zazzabi: 25 ° C (1) ACD
logD 6.19 pH 10; Zazzabi: 25 ° C (1) ACD
logP 6.761± 0.669 Zazzabi: 25 ° C (1) ACD
Mass Intrinsic Solubility 2.0 x 10-4 g/L Zazzabi: 25 ° C (1) ACD
Mass Solubility 0.046 g/L pH da 1; Zazzabi: 25 ° C (1) ACD
Mass Solubility 5.7 x 10-3 g/L pH da 2; Zazzabi: 25 ° C (1) ACD
Mass Solubility 7.6 x 10-4 g/L pH da 3; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.5 x 10-4 g/L pH da 4; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.0 x 10-4 g/L pH da 5; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.0 x 10-4 g/L pH da 6; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.0 x 10-4 g/L pH da 7; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.0 x 10-4 g/L pH da 8; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.5 x 10-4 g/L pH da 9; Zazzabi: 25 ° C (1) ACD
Mass Solubility 7.4 x 10-4 g/L pH 10; Zazzabi: 25 ° C (1) ACD
Mass Solubility 2.0 x 10-4 g/L Ruwan da ba a buƙata ba pH 7.00; Zazzabi: 25 ° C (1) ACD
Solubility na Ciki na Molar 2.4 x 10-7 mol/L Zazzabi: 25 ° C (1) ACD
Solubility na Molar 5.6 x 10-5 mol/L pH da 1; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 7.0 x 10-6 mol/L pH da 2; Zazzabi: 25 ° C (1) ACD

 

Dukiya Daraja Yanayi Source
Solubility na Molar 9.3 x 10-7 mol/L pH da 3; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 3.1 x 10-7 mol/L pH da 4; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 2.5 x 10-7 mol/L pH da 5; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 2.4 x 10-7 mol/L pH da 6; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 2.4 x 10-7 mol/L pH da 7; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 2.5 x 10-7 mol/L pH da 8; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 3.1 x 10-7 mol/L pH da 9; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 9.0 x 10-7 mol/L pH 10; Zazzabi: 25 ° C (1) ACD
Solubility na Molar 2.4 x 10-7 mol/L Ruwan da ba a buƙata ba pH 7.00; Zazzabi: 25 ° C (1) ACD
Nauyin Kwayoyin Halitta 818.89    
pKa 9.55± 0.10 Mafi yawan zafin jiki: 25 ° C (1) ACD
pKa 3.45± 0.70 Mafi Asalin Zazzabi: 25 ° C (1) ACD

(1) An ƙididdige ta ta amfani da Ci gaban Chemistry na Babba (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Lipinski

Dukiya Daraja Yanayi Source
Ƙimar Rarraba Kyauta 21   (1) ACD
H Masu karɓa 14   (1) ACD
H Masu Ba da taimako 1   (1) ACD
H Donor/Acceptor Sum 15   (1) ACD
logP 6.761± 0.669 Zazzabi: 25 ° C (1) ACD
Nauyin Kwayoyin Halitta 818.89    

(1) An ƙididdige ta ta amfani da Ci gaban Chemistry na Babba (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Tsarin Yanayi

Dukiya Daraja Tushen yanayi
Wuri Mai Girma 164 A2 (1) ACD

(1) An ƙididdige ta ta amfani da Ci gaban Chemistry na Babba (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)

Spectra da aka annabta

Spectra akwai
1 H NMR
13 C NMR

Bayanin Hazard na GHS

Tushen Bayanin Hazard na Code
H302 Yana da illa idan an haɗiye shi Rarraba Hukumar Kula da Sinadarai ta Turai (ECHA) & Lakabi

Inventory - Sanarwa Rarrabawa da lakabi - sanarwar da aka fi sani, Hukumar Kula da Sinadarai ta Turai (ECHA)

Rabewa&Kyakkyawan Lakabi - Faɗakarwar Rarrabawa da Lakabi - sanarwa mafi mahimmanci


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